Intraspinal microstimulation produces over-ground walking in anesthetized cats
نویسندگان
چکیده
منابع مشابه
Modularity of motor output evoked by intraspinal microstimulation in cats.
We studied the forces produced at the cat's hindpaw by microstimulation of the ipsi- and contralateral lumbar spinal cord in spinal intact alpha-chloralose anesthetized (n = 3) or decerebrate (n = 3) animals. Isometric force and EMG responses were measured at 9-12 limb configurations, with the paw attached to a force transducer and with the hip and femur fixed. The active forces elicited at dif...
متن کاملCharacteristics and mechanisms of locomotion induced by intraspinal microstimulation and dorsal root stimulation in spinal cats.
Intraspinal microstimulation (ISMS) through a single microelectrode can induce locomotion in cats spinalized at T(13) 1 wk before (untrained) or after 3-5 wk of treadmill training. Here we study the optimal parameters of ISMS and the characteristics of locomotion evoked. ISMS was applied in the dorsal region of segments L(3)-S(1) at different lateralities (midline to 2.5 mm) and after an intrav...
متن کاملBinding in Anesthetized Cats
The effects of halothane and ketamine anesthesia on [ 11 C]raclopride binding were assessed in the cat striatum at basal conditions and after drugor depolarization-induced dopamine (DA) release using Positron Emission Tomography. At baseline, Scatchard analyses revealed that the higher [ 11 C]raclopride binding found under halothane anesthesia was mainly attributable to a higher radioligand app...
متن کاملReturning Independence to the Paralyzed: Intraspinal Microstimulation Prosthetics
University of Pittsburgh, Swanson School of Engineering 11.01.2016 1 Disclaimer—This paper partially fulfills a writing requirement for first year (freshman) engineering students at the University of Pittsburgh Swanson School of Engineering. This paper is a student, not a professional, paper. This paper is based on publicly available information and may not provide complete analyses of all rele...
متن کاملMRI-Guided Stereotactic System for Delivery of Intraspinal Microstimulation.
STUDY DESIGN Laboratory/animal-based proof of principle study. OBJECTIVE To validate the accuracy of a magnetic resonance imaging (MRI)-guided stereotactic system for intraspinal electrode targeting and demonstrate the feasibility of such a system for controlling implantation of intraspinal electrodes. SUMMARY OF BACKGROUND DATA Intraspinal microstimulation (ISMS) is an emerging preclinical...
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ژورنال
عنوان ژورنال: Journal of Neural Engineering
سال: 2016
ISSN: 1741-2560,1741-2552
DOI: 10.1088/1741-2560/13/5/056016